Clinical Endocannabinoid Deficiency (CED)

The CED is a theory developed in 2001 by Dr. Ethan B. Russo, MD, a board-certified neurologist, psychopharmacology researcher, and former Senior Medical Advisor to GW Pharmaceuticals. Dr. Russo believes there is an underlying endocannabinoid “tone” that reflect the levels of AEA and 2-AG. Two natural produced molecules, known as endocannabinoids. The theory proposes that sometimes the “tone” drops out of balance causing an “imbalance” or “deficiency”. This deficiency can then manifest itself in psychosomatic symptoms like migraines, anxiety, and sleeping issues. In order remedy this deficiency by bring the “tone” back in balance the use of phytocannabinoids and synthetic cannabinoids are recommended.

More on the EndoCannabinoid System (ECS)

Cannabinoids

What are Cannabinoids?

God's gift to humans and dogs.

cannabinoids

cannabidiol the "wonder molecule" was discoverd in 1942

endocannabinoids(internal) phytocannabinoid(plant) syntehetic(human-made)

113 phytocannabinoids found in the cannabis sativa plant

40% of plant extract

empirical evidence

PubMed studies on Cannabis

PubMed studies for treatment for

Endocannabinoid (EC) System

physiologic system

centeral to health and healing of every human and most animals

regulates internal and cellular homeostasis

system consists of

  • receptors
  • endogenous ligands
  • ligand metabolic enzymes

endocannabinod tone

2 receptor types

  • CB1 - nervous system, connective tissues, gonads, glads, and organs (brain)
  • CB2 - immune system (spleen) anti-imflammatory

GPCR - G Protein-coupler receptor

Types of Cannabinoids

endocannabinoids

Molecule type:natural

anandamide (AEA)

2-arachidonoylglycerol (2-AG)

phytocannabinoids

Molecule type: plant

Phytocannabinoids are plant substances that stimulate cannabinoid receptors

    top 3
  • cannabinol (CBN)
  • cannabidiol (CBD)
  • delta-9-tetrahydrocannabinol (THC)

syntehetic

Molecules type: pharmacotical > pharmaceutical

dronabinol (Marinol)

nabilone (Cesanmet)

(therapeutic) (long term health issues)

physiological & mental processes

non habit-forming | no psychoactive properties

daily use | will not impair user

liquid | 3rd party tested | soil 2 oil

THE TEAM

The ones who run this company

IHEMPAWA

Industrial Hemp Association of Washington

IHEMPAWA

Promoting the research and development of Industrial Hemp as an agricultural crop in Washington State as a viable and sustainable ultimate renewable natural resource through the Industrial Hemp Research Pilot Program.

Trace Analytics

Trace Analytics

When accuracy matters

Our dedicated laboratory staff is focused on partnering with clients to ensure the best possible outcomes. From early product assessment, research and development or final I-502 testing, Trace Analytics delivers.

Bright Day CBD

Bright Day CBD

Hemp Derived CBD products for you, your family, and your pets.

Our passion for excellence has driven us from the beginning and continues to drive us into the future. The team at Bright Day knows that every product counts, and strives to make the entire shopping experience as rewarding and fun as possible. Drop by our store soon to see the variety of CBD products we carry.

NORML

NORML

Working to reform marijuana laws

NORML's mission is to move public opinion sufficiently to legalize the responsible use of marijuana by adults, and to serve as an advocate for consumers to assure they have access to high quality marijuana that is safe, convenient and affordable.

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